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Cloudy (or CLOUDY) is a code to model the effect of gas and plasma on spectra, in particular, the addition of emission lines. It is used to model gas between stars, e.g., ISM, IGM, ICM, photospheres, sources of EMR such as accretion disks and active galactic nuclei (AGNs), and the effect intervening clouds (e.g., HI regions).
TPCI (for The PLUTO-Cloudy Interface) is interface code to use Cloudy with the PLUTO magnetohydrodynamics (MHD) simulation code.